COX-2 Inhibitor Drug Review

Supplemental results to the large COX-2 inhibitor review in JAMA: "Adverse Effects of Cyclooxygenase-2 Inhibitors on Renal and Arrhythmia Events: Meta-Analysis of Randomized Trials"

Official supplemental website authorized by the executive editors of Journal of the American Medical Association

Full text of study available via JAMA

Valdecoxib and Parecoxib Tests for Publication Bias

TESTS FOR PUBLICATION BIAS:

RENAL COMPOSITE

Begg's Funnel Plot, overall (Begg's Test, p=0.90; Egger's Test p=0.31)

Begg's Funnel Plot, among journal published articles (Begg's Test, p=0.44; Egger's Test p=0.43)

Begg's Funnel Plot, among non-journal trial reports (Begg's Test, p=0.94; Egger's Test p=0.48)

Egger's Plot, overall (Egger's Test, p=0.31)

ARRHYTHMIA

Begg's Funnel Plot, overall (Begg's Test, p=0.37; Egger's Test, p=0.53)